Selective Allodepletion: Have We Finally Found the Holy Grail?

Selective allodepletion: have we finally found the holy grail?

Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment option for patients with hematologic malignancies and nonmalignant disorders of hematopoiesis. Outcomes of allogeneic HSCT have improved steadily over the decades [1]. However, significant challenges remain. One of these challenges is the so-called Holy Grail of stem cell transplantation immunology: to...

Statins: have we found the Holy Grail?

In coronary artery disease, cardiovascular risk factors are the main targets for primary and secondary prevention. Statins prevent cardiovascular events in patients at risk. However, despite the proven efficacy and safety of statins, relevant side effects exist and should be considered when treating patients.

Sleeve gastrectomy: have we finally found the holy grail of bariatric surgery? A review of the literature.

OBJECTIVE Laparoscopic sleeve gastrectomy has become one of the most commonly performed bariatric operations. It is essentially a restrictive bariatric operation; however, a series of hormonal changes occurring postoperatively contribute to decreased appetite and reduced food intake. PATIENTS AND METHODS This is a literature review of recent articles published on Pubmed, Medline and Google Sc...

Multidetector CT coronary angiography: have we found the holy grail of non-invasive coronary imaging?

Is technology about to deliver on the long awaited goal of effective non-invasive methods for visualising and assessing coronary arteries?

Visceral analgesics and functional dyspepsia: have we found the Holy Grail?